Resources for you
and your patients
with APDS
If you suspect your patient
has APDS, it’s time to order
a sponsored genetic test*
A genetic test can give you a definitive
APDS diagnosis. Visit navigateapds.com to learn more.
APDS diagnosis. Visit navigateapds.com to learn more.
*Eligibility criteria apply.
Find an APDS expert
APDS is a rare, genetic inborn error of immunity (IEI), and as a result, a limited number of clinicians have had first-hand experience with APDS.
If you are interested in finding a medical professional who has experience with diagnosing and managing APDS, this tool may be able to help.
If you are interested in finding a medical professional who has experience with diagnosing and managing APDS, this tool may be able to help.
View videos and download materials to help address any questions you or your patients might have about Joenja and/or APDS.
Joenja overview for healthcare professionals
A comprehensive brochure providing a brief introduction to APDS, and a detailed description of Joenja that includes an explanation of how Joenja works, the clinical data on the efficacy and safety of Joenja, as well as Joenja dosing and administration information.
Joenja brochure for patients and caregivers
A brochure containing important information for patients and caregivers to know about Joenja, including how and when to take Joenja tablets, what to expect with Joenja, as well as information about patient support services.
Get to know APDS Assist
Find out more about how APDS Assist works to support you and your patients by watching this short video.
Get to know our ACEs Video
Learn how ACEs get patients started with confidence and partner with them and you throughout the Joenja treatment journey.
Mechanism of action video
Watch Joenja in action and gain a clearer understanding of how Joenja targets the underlying immune defect in APDS.
Reminder tone
Download the free Joenja reminder tone, to set and receive an audio reminder when it’s time for you to take your Joenja tablet.
APDS Expert Locator Tool
A tool enabling patients and caregivers to find medical professionals with expertise in diagnosing and treating APDS. Additionally, APDS experts can list their information in the locator tool.
Joenja® patient case-vignettes
Explore patients’ experiences with Joenja to gain insights about the treatment and learn how it impacted patients with APDS who were observed for 6 years.
Learn about APDS and Joenja®
Dr Hartog, a leading allergy and immunology specialist and clinical expert on APDS, discusses a real life patient case and the path to diagnosis, complexities of APDS, clinical trial results for Joenja® and resources to support you and your patients.
Joenja® targeting the mechanics of APDS
Dr Mehta, a Hematologist/Oncologist and leading clinical expert on APDS, explains how Joenja targets the mechanics of APDS to help restore immune balance. He presents a real-life patient case and clinical trial results for Joenja®.
Global Genes
Genome
Delivering telehealth genetic counseling and software solutions that increase access to genetic services and support patient decision-making.
Primary Immune Deficiency Treatment Consortium
Working together to improve the outcome for patients with rare, life-threatening, inherited disorders of the immune system.
Rare Revolution Magazine
Working to bring about a dramatic and wide-reaching change in conditions and attitudes for the rare disease community.
National Organization for Rare Disorders (NORD)
Advancing practical, meaningful and enduring change so people with rare diseases can live their fullest and best lives.
International Primary Organisation for Primary Immunodeficiencies
A nonprofit international organization and the leading advocate for primary immunodeficiency patients worldwide working in collaboration with patients, doctors, politicians, regulators, pharmaceutical industry, and other relevant stakeholders.
Immune Deficiency Foundation (IDF)
Improving the diagnosis, treatment, and quality of life of people affected by primary immunodeficiency through fostering a community empowered by advocacy, education, and research.
Jeffrey Modell Foundation (JMF)
A global nonprofit dedicated to early diagnosis, treatment, and ultimately, future cures for primary immunodefiency through awareness, advocacy, and research.
About APDS
APDS is a rare, primary immunodeficiency. Hyperactivity along the Pl3Kδ signaling pathway disrupts immune cell balance, causing immune deficiency and immune dysregulation.1-4
About
APDS Assist
This patient support program is designed specifically for your patients with APDS.
References: 1. Joenja (leniolisib). Prescribing information. Pharming Healthcare, Inc; 2023. 2. Maccari ME, Abolhassani H, Aghamohammadi A, et al. Disease evolution and response to rapamycin in activated phosphoinositide 3-kinase δ syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry. Front Immunol. 2018;9:543. doi:10.3389/fimmu.2018.00543 3. Angulo I, Vadas O, Garçon F, et al. Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage. Science. 2013;342(6160):866-871. doi:10.1126/science.1243292 4. Rao VK, Webster S, Šedivá A, et al. A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome. Blood. 2023;141(9):971-983. doi:10.1182/blood.2022018546
