Twenty-seven Joenja patients were receiving IRT at the start of the OLE study

  • Four patients had been IRT free for 1 to 2.5 years
  • The median time to IRT reduction was 12.1 months and the median time to IRT discontinuation was 11.9 months

Not actual patients.

IRT use was captured by the investigator as concomitant medication at each study visit per protocol in this OLE study. IRT was not prespecified as an end point or analysis. This is an observation from a post hoc analysis and no determination of statistical significance can be made and no conclusions should be drawn.
One of these patients had a subsequent one-time dose of IRT.